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Literature summary extracted from

  • Tomatsu, S.; Montano, A.M.; Gutierrez, M.; Grubb, J.H.; Oikawa, H.; Dung, V.C.; Ohashi, A.; Nishioka, T.; Yamada, M.; Yamada, M.; Tosaka, Y.; Trandafirescu, G.G.; Orii, T.
    Characterization and pharmacokinetic study of recombinant human N-acetylgalactosamine-6-sulfate sulfatase (2007), Mol. Genet. Metab., 91, 69-78.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.6.4 overexpression in chinese hamster ovary cells Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.6.4 60000
-
 2 * 60000 Da Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.4 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.4 two-step affinity chromatography, purified 1317-fold, 71% yield Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.1.6.4 4°C, 25 mM sodium acetate, 1 mM beta-glycerophosphate buffer, pH 5.5, several months, no significant loss of acitivity Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.4 N-acetylgalactosamine 6-sulfate + H2O
-
 Homo sapiens N-acetylgalactosamine + sulfate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.6.4 homodimer 2 * 60000 Da Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.6.4 GALNS
-
 Homo sapiens
3.1.6.4 N-acetylgalactosamine-6-sulfate sulfatase recombinant Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.6.4 5 6 purified recombinant enzyme Homo sapiens